Sister projects

Sister projects

HORIZON-CL4-2024-RESILIENCE-01- 36

Together towards next-generation regenerative medicine

TEN4CARE is part of a cluster of six European projects sharing the same call, the same scientifichorizon, and the same commitment: transforming the treatment of chronic conditions throughadvanced,intelligent biomaterials.

ABOUT THE ALLIANCE

One European cluster, six complementary solutions

The six projects funded under the Advanced biomaterials for the Health Care topic (HORIZON-CL4-2024-RESILIENCE-01-36)are not just parallel endeavours — they are strategic collaborators. Each addresses a different pathology — tendon, bone,chronic wound, intestinal mucosa, osteonecrosis, or cardiac arrhythmia — yet all share technological platforms, regulatorychallenges, and clinicaltranslation hurdles. Working together is not optional; it is the most effective way to accelerate impact

SISTER PROJECTS

Meet TEN4CARE’s five sister projects

HydroHeal

Bone regeneration · vertebral and alveolar fractures

Develops multi-functional, self-solidifying hydrogels with controlled-release microparticles to treat complex bone fractures caused by osteoporosis, cancer, or trauma — reducing infection risk and improving recovery outcomes.

KEY SYNERGIES WITH TEN4CARE
Bioactive hydrogel design, Safe and Sustainable by Design (SSbD) frameworks, guided regeneration mechanisms, and controlled drug delivery strategies.

GreenNanoBone

Jaw osteonecrosis · cancer patients

Creates biocompatible, antimicrobial 4D hydrogels synthesised from plant-based nanoparticles (potato industry waste), AI-optimised, for the prevention and treatment of medication-related osteonecrosis of the jaw (MRONJ) in cancer patients.

KEY SYNERGIES WITH TEN4CARE
SSbD principles, nanomaterial characterisation, sustainable manufacturing, and clinical translation to Phase I trials.

DAEDALUS

Intestinal diseases · colorectal mucosa and submucosa

Designs injectable 4D biomaterials. Enriched with patient-derived cells to replace damaged colorectal mucosal and submucosal tissue in conditions such as ulcerative colitis and familial adenomatous polyposis, avoiding invasive surgery.

KEY SYNERGIES WITH TEN4CARE
In situ biofabrication, autologous cell integration, stimuli-responsive materials, and minimally invasive surgical approaches.

INJECTHEAL

Chronic wounds · deep and hard-to-reach tissue

Develops a green 4D self-healing injectable hydrogel based on functionalised pectin and gelatin, integrating antibacterial, anti-inflammatory, and pro-angiogenic agents for comprehensive treatment of deep chronic wounds — a condition affecting over 305 million people worldwide.

KEY SYNERGIES WITH TEN4CARE
Minimally invasive delivery, controlled bioresorption, industrial scalability, and commercial exploitation pathways.

NANOBEAT

Cardiac arrhythmias · atrial fibrillation and bundle branch blocks

Restores cardiac conductivity in atrial fibrillation and left bundle branch blocks using noble metal-based nano-biomaterials, developed in partnership with Medtronic Bakken Research Center, combining advanced nanotechnology with materials engineering.

KEY SYNERGIES WITH TEN4CARE
Physical and electromagnetic stimulation, nanocomposite engineering, and functional tissue restoration strategies.

JOINT INITIATIVES

What we build together

Structured clustering goes well beyond shared visibility. Our joint work targets concrete, high-impact deliverables that no single project could achieve alone.

Exploring public policy avenues

Potential joint development of a Policy Brief addressed to EU health authorities, aimed at providing strategic recommendations on regulatory frameworks, reimbursement pathways, and future research funding priorities for advanced biomaterials.

Systematic technical knowledge exchange

Structured sharing of expertise on smart biomaterials, application of SSbD guidelines to the medical sector, and integration of digital twins and AI-assisted manufacturing across consortium partners.

Coordinated international presence

Joint representation at major scientific conferences — TERMIS, ESB, World Biomaterials Congress — alongside cross-project social media campaigns to amplify the collective reach and impact of the cluster.

Follow our European cluster’s journey

Consortium updates, joint news and conference presence.

Follow our European cluster’s journey

Consortium updates, joint news and conference presence.

* Links to sister project websites and social media channels will be updated as they become available. Several projects launched in 2025 and are in the early stages of establishing their online presence.

Funded by the European Union. TEN4CARE has received funding from the European Union’s Horizon Europe research and innovation programme under grant agreement No. [Grant No.]. Views and opinions expressed are however those of the author(s) only and do not necessarily reflect those of the European Union or the European Research Executive Agency (REA). Neither the European Union nor the granting authority can be held responsible for them.